GPNMB paper in Neurogenetics


Just out in Neurogenetics, Megha Murthy and Daniah Trabzuni from the lab have published a study of a region on chromosome 7 that is associated with Parkinson’s disease in the most recent genome wide association study. By looking at gene expression in the region, they identified variation in GPNMB as the most likely cause of that association – you can read all about it here.

James Parkinson article

My article on James Parkinson has been reposted by the Parkinson’s Life website, available at the link below:

The original article, particularly pertinent in this year of the bicentenary of James Parkinson, is available to download for free from the Journal of Parkinson’s disease:

And for those who are really interested, these are links to reprints of the Essay on the Shaking Palsy:

AD/PD – Vienna 2017


Claudia Manzoni, Daniah Trabzuni and Megha Murthy from the group are all in Vienna this week at the AD/PD meeting. Daniah and Claudia are giving talks (Claudia at the International Parkinson’s Disease Consortium meeting), and Megha is giving a poster presentation about her research into the PD risk locus on chromosome 7 – which has just been accepted for publication (more details on this soon). I’m looking after the lab, waiting for the arrival of a new laboratory member with a due date of the 16th of April.

200 Years of Parkinson’s disease

Many thanks to the Reading University Psychology society for inviting me to speak at their Brain Awareness week symposium on Parkinson’s disease. I talked about some of the milestones in 200 years of Parkinson’s research, since James Parkinson wrote his essay on the Shaking Palsy (the Youtube video of this is above). Coincidently, the Journal of Parkinson’s disease has an open access issue out now that covers a number of these milestones (click on the link below for access).

Biochemical Society Transactions paper


Claudia Manzoni in the lab has just had a review article published in Biochemical Society Transactions, a follow up from the LRRK2 to meeting that myself, Elisa Greggio and Kirsten Harvey organised last year. An excellent summary of some of the latest thinking on what LRRK2 is doing in the cell.

Read all about it on the link below, freely available.