I’ve tweeted about this already, but worth highlighting again. I’ve written a piece for the Conversation on the late Arvid Carlsson and the contribution that his work on dopamine made to the development of drugs for Parkinson’s disease. Read all about it below:
I talked to year 12 students at William Borlase’s school in Marlow today, covering a career in biomedicine and some edited highlights from the research in the group. A really engaging group of students, and as always some excellent questions.
We have a fully funded, four year studentship available to study the structural biology of the ROCO proteins in collaboration with the Diamond Light Source. Details below, and feel free to email me (email@example.com) if you have any questions.
I was delighted to receive a research engagement and impact award here at the University of Reading this evening, on behalf of everybody involved in the Parkinson’s 200 events held last year to make the bicentennial of the publication of James Parkinson’s essay on the shaking palsy. Many thanks to Sally Bromley, Chrystalina Antoniades and everyone at the Oxford Parkinson’s UK branch!
Lovely image from Susanne Herbst at the Crick gracing the cover of EMBO Journal this week, taken from the paper on LRRK2 and mycobacterial biology.
I spent this afternoon at Garth Hill College in Bracknell, talking to year 10 students about how our understanding of our genomes has been revolutionised over the past decade, and how this will impact on their futures.
Just out in BMC Genomics, Claudia’s study on how the inherited forms of Parkinson’s disease form biological networks centred around key processes.
I spent today at the Instituto de Medicina Molecular here in Lisbon, giving a talk about some of the work we’ve been doing in the lab investigating LRRK2 and taking part in a thesis committee for a former Erasmus student in the lab, Marie Bordone (Marie is now a PhD student here at the IMM). And I also got to eat some custard tarts.
Claudia from the group is an author on a paper just out in Cancer Research showing that mutations in the MAPT gene, which codes for the protein tau, can predispose to cancer. These mutations have long been known to cause dementia, so this is a fascinating insight into the underlying changes in biology shared by these very different diseases.
And just out in EMBO Journal, an article from Max Gutierrez and Matthias Trost (to which I contributed) investigating how LRRK2 is involved in the biology of Mycobacteria. A fascinating paper that has been over five years in the making, and one that has some very interesting implications for LRRK2 and for Parkinson’s disease. Read all about it here: