Diamond PhD studentship application link

Diamond standard logo with www

For those looking to apply to the Diamond Light Source/University of Reading studentship, please click on the link below and follow the links through to the University of Reading RISIS application system. You should apply for a PhD in Pharmacy, quoting the reference GS18-026.

http://www.jobs.ac.uk/job/BIH640/diamond-light-source-phd-studentship-structural-biology-of-complex-enzymes-in-parkinsons-disease/

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ULK1 and LRRK2

UntitledJust out in Bioscience Reports, Claudia from the group has published a paper suggesting that chronic inhibition of LRRK2 can alter phosphorylation of ULK1 – an important regulator of macroautophagy.

Read all about it here:

http://www.bioscirep.org/content/early/2018/03/20/BSR20171669

Science fair at Maiden Erlegh School

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On Friday I was privileged to act as judge for the Maiden Erlegh school science fair, where students from across the year groups had worked on topics as wide ranging as “the science of dragons” to “what is it like to be colour blind?”. I was really impressed by the standard of the presentations, the only shame was that I had to choose winners for each key stage – the students made my job very difficult!

Diamond studentship – deadline extended!

Diamond standard logo with www

The deadline for the four year PhD in collaboration with Diamond Light Source has been extended to the end of the month! The project will use state of the art structural biology approaches to shine a light on the biology of the ROCO proteins, such as LRRK2, and help us understand how this protein is involved in Parkinson’s disease.

See link below for details.

https://www.findaphd.com/search/ProjectDetails.aspx?PJID=96113

ROCO paper in Proteomics

proteomics

Just out in Proteomics, James Tomkins and Claudia Manzoni from the group have published a fascinating study on the comparative interactomes of the ROCO proteins (including LRRK2). This study sheds light on some of the common pathways and different functions of these proteins. The abstract is now online, and I will update once the open access paper is available.

http://onlinelibrary.wiley.com/doi/10.1002/pmic.201700444/abstract